Poly-L-Lactic Acid (PLLA), is a substance which has been used for over 30 years as medical material for tissue regeneration, suture and surgical sealant and more recently was FDA approved in 2009 as an injectable facial rejuvenation treatment to stimulate. This new generation polymer is extracted from Alpha Hydroxy Acid (AHA) which is known for its absorbability and biodegradability properties.
Now available in a thread form, practitioners can directly address the structure of the face for an immediate lifting effect, accompanied by a longer-term regeneration of collagen and natural volume. Biodegradation of PLLA occurs through a process of hydrolysis over a time period of between six to eight months while the aesthetic duration of threading results has been found to last between 18-24 months.
Absorbable poly(glycolide/l-lactide) surgical suture. An absorbable poly(glycolide/l-lactide) surgical suture (PGL suture) is an absorbable sterile, flexible strand as prepared and synthesized from homopolymers of glycolide and copolymers made from 90 percent glycolide and 10 percent l-lactide and is indicated for use in soft tissue approximation.
A PGL suture meets United States Pharmacopeia (U.S.P.) requirements as described in the U.S.P. “Monograph for Absorbable Surgical Sutures;” it may be monofilament or multifilament (braided) in form; it may be uncoated or coated, and it may be undyed or dyed with an FDA-approved color additive.
THE AESTHETIC APPLICATION
Wrinkles/Lines of Langar
Cheek Augmentation Masseter/Jawline
Neck/Submental and Jowl
Lactic acid is present in the body is L (+) isomer and do not mix the L-form and D-type. This is because the skin can become wavy when put on the skin due to different decomposition time. Poly (L-Lactic acid) (PLLA) is available for uptake, and synthetic polymer suitable for the living body. It is decomposed into water and carbon dioxide and lactic acid. In addition, safe and does not require an allergy test before clinical use.
Already used in the medical industry as a material for sealing a product to be absorbed into the body has been used for over 30 years or coating agent is used in the wound. PLLA is a degradation period of about one year, one year to maintain the elasticity and wrinkle improvement.
Comparing the tensile strength of PLLA with PDO, PDO is short, the initial tensile strength of higher decomposition period in vitro experiments. On the other hand the initial tensile strength of PLLA is weak, the decomposition until about 40 weeks can be sure that you did not occur entirely.